Degradation rates and products of fluticasone propionate in alkaline solutions
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چکیده
منابع مشابه
Degradation rates and products of fluticasone propionate in alkaline solutions
The apparent degradation rate constant of fluticasone propionate (FLT) in 0.1 M NaOH:methanol=1:1 at 37 °C was previously reported to be 0.169±0.003 h-1, and four degradation products (products 1-4) were observed in the solution. The aims of the present study were to assess the degradation rates of FLT in other alkaline solutions and clarify the chemical structures of the four degradation produ...
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ژورنال
عنوان ژورنال: Journal of Pharmaceutical Analysis
سال: 2017
ISSN: 2095-1779
DOI: 10.1016/j.jpha.2017.03.010